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altImaging in vivo

Optical Coherence Tomography is analogous to ultrasound, but employs the time-of-flight of backscattered photons rather than sound. We have developed a working freespace Optical Coherence Tomography (OCT) prototype, and recently developed a conical fibre tip based system. With our objective based system, we have we have achieved an axial resolution of 14 µm, a lateral resolution of 5 µm, and a penetration depth of 200 µm to 3 mm.

Key References

(If desired, all references and pdfs may be downloaded en masse in an Endnote formatted zip file)

In-fiber common-path optical coherence tomography using a conical-tip fiber, K. M. Tan, M. Mazilu, T. H. Chow, W. M. Lee, K. Taguichi, B. K. Ng, W. Sibbett, C. S. Herrington, C.T. A. Brown, and K. Dholakia, Opt. Express 17, 2375-2384 (2009) (pdf)